Assessment of absolute oral bioavailability of linezolid tablets in Chinese healthy male volunteers 

AIM:Linezolid is a member of oxazolidinones,which is a novel class of antibiotics.The study is to determine the absolute bioavailability of linezolid tablets...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(15)| 被引次数(0)

Loss of Aβ-nerve endings associated with the Merkel cell-neurite complex in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis 

The Merkel cell-neurite complex initiates the perception of touch and mediates Ab slowly adapting type I responses.Lichen planus is a chronic inflammatory autoi...
《International Journal of Oral Science》  2016年 第01期 下载次数(23)| 被引次数(4)

Increased virulence of the oral microbiome in oral squamous cell carcinoma revealed by metatranscriptome analyses 

Oral squamous cell carcinoma(OSCC) is the most prevalent and most commonly studied oral cancer. However, there is a void regarding the role that the oral microb...
《International Journal of Oral Science》  2018年 第04期 下载次数(12)| 被引次数()

Pharmacokinetics and Safety of Febuxostat Following a Single and Multiple Oral Doses in Healthy Chinese Volunteers 

The pharmacokinetics and safety of febuxostat were assessed in healthy Chinese volunteers.In the single-dose study,a randomized open-label,2-way crossover de...
第十三次全国临床药理学学术大会论文汇编  2012-10-26 下载次数(20)| 被引次数(0)

Periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis 

Oral lichen planus (OLP) is a chronic inflammatory disease that is frequently detected in oral tissues. The aim of our study was to identify the prevalence of t...
《International Journal of Oral Science》  2013年 第02期 下载次数(54)| 被引次数(14)

Safety and Immunogenicity of oral,live trivlent human-ovine rotavirus 

Objective Rotavirus is the leading cause of severe diarrhea in infants and young children worldwide.Previous studies of a live trivlent human-ovine reassorta...
2012全国临床微生物与感染免疫学术研讨会论文集  2012-10-13 下载次数(2)| 被引次数(0)

Salivary mycobiome dysbiosis and its potential impact on bacteriome shifts and host immunity in oral lichen planus 

The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal–bacterial and fungal–immune system interactio...
《International Journal of Oral Science》  2019年 第03期 下载次数(4)| 被引次数(0)

Characterization of oral yeasts isolated from healthy individuals attended in different Colombian dental clinics 

The aim of this study was to identify the most frequent yeasts in the oral cavity of adult individuals without immune disorders and to associate the presence of...
《The Journal of Biomedical Research》  2019年 第05期 下载次数(1)| 被引次数()

Post-dose 12-hour trough concentration of mycophenolate mofetil co-administrated with cyclosporine in dog 

Mycophenolate mofetil (MMF) is a pro-drug for mycophenolic acid (MPA) which reduces the likelihood of allograft rejection after renal transplantation. It was kn...
《畜牧与兽医》  2012年 第S2期 下载次数(8)| 被引次数(0)

Semaphorin 4D-plexin-B2 signal orchestrates CD8~+ T cell proliferation and activation in the pathogenesis of oral lichen planus 

Oral lichen planus(OLP) is among the most common T cell-mediated autoimmune disorders in oral cavity.Not only T cells infiltration is a distinguishing histopath...
第十二届全国免疫学学术大会壁报交流集  2017-10-26 下载次数(10)| 被引次数()

Pharmacokinetic parameters of losartan and losartan/hydrochlorothiazide tablets in healthy chinese male volunteers 

OBJECTIVE To evaluate and compare the of Losartan and Losartan/Hydrochlorothiazide combination tablets in healthy chinses male volunteers.METHODS Both studie...
中国药理学会第十一次全国学术会议专刊  2011-09-23 下载次数(10)| 被引次数(0)

Fasting plasma levels of nesfatin-1 in patients with type 1 and type 2 diabetes mellitus and the nutrient-related fluctuation of nesfatin-1 level in normal humans 

The novel satiety factor nesfatin-l has been shown to decreases food intake and body weight in rodents after i.cv.injection.However,no further developments r...
Proceedings of the 8th Biennial Conference of the Ch…  2009-11-07 下载次数(41)| 被引次数(0)

基于高通量测序的肠化生患者上消化道菌群研究 

研究背景:胃黏膜肠上皮化生(Gastric intestinal metaplasia,GIM)是由包括潘氏细胞、杯状细胞和吸收细胞组成的肠黏膜取代了正常的胃黏膜上皮细胞的一种疾病。它是胃癌(gastric cancer,GC)发生路径中的一重要癌前病变,研究表明胃黏膜菌群、口腔菌群均是胃癌发生的潜在风险因素,胃肠上皮...
山东大学  博士论文  2019年 下载次数(160)| 被引次数()

Research on the pharmacokinetics of single dose and multipledose of gemifloxacin in healthy Chinese male subjects 

AIM:To investigate the pharmacokinetics and safety of gemifloxacin in healthy Chinese subjects and provide some theoretic bases for its reasonable applicatio...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(2)| 被引次数(0)

Safety of fluralaner chewable tablets(Bravecto ~(TM)),a novel systemic antiparasitic drug,in dogs after oral administration 

Background:Fluralaner is a novel systemic insecticide and acaricide that provides long acting efficacy in dogs after a single oral treatment.This study investig...
中国畜牧兽医学会兽医药理毒理学分会第十五次学术讨论会…  2019-10-13 下载次数(2)| 被引次数()

共找到相关记录35条123下一页