CCR5 gene expression in fulminant hepatitis and DTH in mice 

CCR5geneexpressioninfulminanthepatitisandDTHinmiceGUOBaoYu1,ZHANGSuYing2,NaofumiMukaida3,AkihisaHarada3,KoujiKuno3,WANGJian...
《世界胃肠病学杂志》  1998年 第01期 下载次数(12)| 被引次数(0)

Activated NKT Cells Facilitated Functional Switch of Myeloid-derived Suppressor Cells at Inflammation Sites in Fulminant Hepatitis Mice 

Myeloid-derived suppressor cells(MDSCs) confer immunosuppressive properties,but their roles in fulminant hepatitis have not been well defined.In this study,we s...
浙江省免疫学会第十次学术大会论文集  2016-08-05 下载次数(1)| 被引次数()

Interference with novel gene KCTD9inhibits NK cell activation and ameliorates Murine Hepatitis Virus Type 3-induced fulminant hepatitis in BALB/cJmice 

Background/aims:Our previous reports,both experimental and human studies,have shown the novel geneKCTD9 contributed to liver injuiythrough hepatic NK cell ac...
第三届全国病毒性肝炎慢性化重症化基础与临床研究进展学…  2013-08-29 下载次数(5)| 被引次数(0)

CD4~+Foxp3~+ Tregs protect against innate immune cell-mediated fulminant hepatitis in a C57BL/6 mice model 

Background and Aims:Foxp3~+Tregs are important for maintaining homeostasis by controlling excessive immune responses that cause serious tissue damage;yet,relati...
第九届全国免疫学学术大会论文集  2014-10-18 下载次数(12)| 被引次数(0)

Enhanced IL-6 levels during viral fulminant hepatitis but it does not play an essential role in the pathogenesis 

研究背景:Viral fulminant hepatitis(FH)is a serious liver disease and patients require immediate hospitalizationInflammation accelerates the pathogenesis but lacking...
第九届全国免疫学学术大会论文集  2014-10-18 下载次数(7)| 被引次数(0)

The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis 

Aim:Viral fulminant hepatitis(FH)is a severe disease with high mortality resulting from excessive inflammation in the infected liver.Clinical interventions have...
第十届全国免疫学学术大会汇编  2015-11-14 下载次数(17)| 被引次数(0)

重症乙型肝炎HBV DNA CP 区及前S区基因变异与河南地区HBV DNA 基因型的研究 

乙型肝炎病毒(HBV)是一种DNA病毒,人类感染HBV后可以表现为不同的临床类型:无症状感染者、急性、慢性、重症乙型肝炎等。其中重症乙型肝炎患者病情凶险,是HBV感染后的重要转归之一,其病死率高,发病机制尚未清楚。现代研究认为重症乙型肝炎的发生,除了和宿主因素有关外,病原学因素是重要影响因素之一。HBV在感染过程中常发...
郑州大学  硕士论文  2004年 下载次数(106)| 被引次数(1)

HMGB1-TLR4-MyD88 Axis Exacerbates Experimental Viral Fulminant Hepatitis 

Aim: Viral fulminant hepatitis(FH) is a serious liver disease with high mortality due to excessive inflammation in liver tissues. The lack of knowledge on infla...
第十一届全国免疫学学术大会摘要汇编  2016-11-04 下载次数(6)| 被引次数(0)

Neutrophil expressed SRA mediated complement activation contributes to the pathogenesis of fulminant hepatitis via potentiating Fgl2/fibroleukin expression 

Objective:Viral fulminant hepatitis(FH)is a potentially fatal disease,and the underlying pathogenesis remains unclear.Scavenger receptor A(SRA)is a pattern r...
第十一届全国免疫学学术大会分会场交流报告集  2016-11-04 下载次数(6)| 被引次数(0)

A novel subset of double negative T cells effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis 

AIMS:The underlying pathogenesis of fulminant viral hepatitis(FVH) has not been fully elucidated.As a subset of regulatory T cells,CD3+CD4-CD8- double negati...
第二届全国病毒性肝炎慢性化重症化基础与临床研究进展学…  2012-04-12 下载次数(5)| 被引次数(0)

Acute renal failure associated with acute non-fulminant hepatitis B 

A 38-year-old female presenting with a high fever of 39 ℃ developed severe liver dysfunction and acute renal failure(ARF).In tests for a hepatitis associated vi...
《World Journal of Hepatology》  2013年 第02期 下载次数(17)| 被引次数(0)

Dietary copper triggers onset of fulminant hepatitis in the Long-Evans cinnamon rat model 

AIM:To investigate the impact of dietary copper given at different time points on the onset of fulminant hepatitis. METHODS:The Long-Evans cinnamon (LEC) rat mo...
《World Journal of Gastroenterology》  2012年 第39期 下载次数(15)| 被引次数(5)

Construction of mTNFR1shRNA Plasmid and its Biological Effects on MHV-3 Induced Fulminant Hepatitis in BALB/cJ Mice 

Previous study on TNFR1-mediated hepatocyte apoptosis has been implicated in the development of fulminant viral hepatitis.To interfere with the potentially effe...
《Virologica Sinica》  2010年 第01期 下载次数(28)| 被引次数(3)

前S2基因变异及HBV特异性免疫复合物在重型乙型肝炎发病中的作用 

重型乙型肝炎是乙型病毒性肝炎的一种临床表现形式,其病情凶险,病死率高,在我国,每年约有1%的乙型肝炎患者发生重型肝炎。重型肝炎的发病机理至今不清,通常认为由宿主免疫状态和病毒两方面决定。 第一部分:HBV前S2基因变异与重型乙型肝炎的相关性 ...
浙江大学  博士论文  2003年 下载次数(152)| 被引次数(0)

Clinical characteristics of fulminant hepatitis in pregnancy 

AIM:To investigate the clinical characteristics of fulminant hepatitis in pregnancy. METHODS:We compared and analyzed the etiology, clinical characteristics,...
《World Journal of Gastroenterology》  2005年 第29期 下载次数(4)| 被引次数(12)

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