Implementation of a reference-scaled average bioequivalence approach for highly variable generic drug products of agomelatine in Chinese subjects 

The aim of this study was to apply the reference-scaled average bioequivalence(RSABE)approach to evaluate the bioequivalence of 2 formulations of agomelatine,an...
《Acta Pharmaceutica Sinica B》  2016年 第01期 下载次数(19)| 被引次数(1)

A contemporary view of bioequivalence and therapeutic equivalence 

Bioequivalence studies play an important role in the drug development as well as during the post-approval peri- od for both new drugs and generic drugs.In pr...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(9)| 被引次数(0)

The study of bioavailability and bioequivalence of oseltamivir in Chinese health volunteers 

Objective To evaluate the bioavailability and bioequivalence of oseltamivir capsule in Chinese health male volunteers.Methods A randomized,two period,two treatm...
《沈阳药科大学学报》  2008年 第S1期 下载次数(31)| 被引次数(0)

Pharmacokinetics and bioequivalence of ranitidine and bismuth derived from two compound preparations 

AIM: To evaluate the bioequivalence of ranitidine and bismuth derived from two compound preparations. METHODS: The bioavailability was measured in 20 healthy...
《World Journal of Gastroenterology》  2006年 第17期 下载次数(60)| 被引次数(4)

Bioequivalence and pharmacokinetics of a compound sustained-release formulation of Nifedipine plus atenolol in healthy subjects 

AIM:Nifedipine and atenolol are the representative drugs for calcium antagonists and β-blockers,their combination use is the highly acclaimed anti-hypertensi...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(6)| 被引次数(0)

The study of bioavailability and bioequivalence of oseltamivir in Chinese health volunteers 

Objective To evaluate the bioavailability and bioequivalence of osehamivir capsule in Chinese health male volunteers.Methods A randomized,two period,two trea...
两岸三地药理学与临床药理学术会议论文集  2008-10-01 下载次数(6)| 被引次数(0)

A Rapid and Simple HPLC Method for theDetermination of Pantoprazole in Human Plasma:Validation and Application to a Bioequivalence Study 

A selective and sensitive HPLC method with rapid sample processing was developed for determi- nation of pantoprazole in human plasma using omeprazole as inte...
2008第十一次全国临床药理学学术大会论文集  2008-09-01 下载次数(7)| 被引次数(0)

Bioequivalence study of fusidicacid suspension in healthy volunteers 

AIM:To study the relative bioequivalence of fusidic acid suspension and its contrastive suspension. METHODS:A single oral dose of 750 mg domestic fusid- ic a...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(6)| 被引次数(0)

Points-to-consider:bioequivalence studies vs.biowaivers 

Bioequivalence is a critical tool that links the results of clinical studies to the pharmaceutical products that have undergone various manufacture changes.A...
中国药理学会临床药理学专业委员会会议暨第十次全国临床…  2007-06-01 下载次数(9)| 被引次数(0)

An improved LC–MS/MS method for the quantification of alverine and para hydroxy alverine in human plasma for a bioequivalence study 

A highly sensitive and selective high performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of al...
《Journal of Pharmaceutical Analysis》  2017年 第02期 下载次数(13)| 被引次数(1)

Application of an LC–MS/MS method for the analysis of amlodipine,valsartan and hydrochlorothiazide in polypill for a bioequivalence study 

A sensitive and selective method has been proposed for the simultaneous determination of amlodipine(AML),valsartan(VAL) and hydrochlorothiazide(HCTZ) in human p...
《Journal of Pharmaceutical Analysis》  2017年 第05期 下载次数(7)| 被引次数()

Determination of torasemide in human plasma and its bioequivalence study by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry 

A sensitive and selective method using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry(HPLC–ESI–MS) to dete...
《Journal of Pharmaceutical Analysis》  2016年 第02期 下载次数(11)| 被引次数(1)

Determination of lercanidipine in human plasma by an improved UPLC–MS/MS method for a bioequivalence study 

An improved and reliable ultra-performance liquid chromatography/tandem mass spectrometry(UPLC–MS/MS) method has been developed and validated for the determinat...
《Journal of Pharmaceutical Analysis》  2016年 第02期 下载次数(5)| 被引次数()

SPE-UPLC-MS/MS assay for determination of letrozole in human plasma and its application to bioequivalence study in healthy postmenopausal Indian women 

A rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS) method is described for determination of letrozole in human p...
《Journal of Pharmaceutical Analysis》  2016年 第04期 下载次数(8)| 被引次数(1)

Improved simultaneous quantitation of candesartan and hydrochlorthiazide in human plasma by UPLC–MS/MS and its application in bioequivalence studies 

A validated ultra-performance liquid chromatography mass spectrometric method(UPLC–MS/MS) was used for the simultaneous quantitation of candesartan(CN) and hydr...
《Journal of Pharmaceutical Analysis》  2014年 第02期 下载次数(15)| 被引次数(5)

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