First evidence of proteinG-binding protein in the most primitive vertebrate:Serum lectin from lamprey(Lampetra japonica) 

Intelectins are a recently identified extracellular animal lectin as a glycan-binding receptors that recognize glycan epitopes on foreign pathogens and in the h...
遗传学进步促进粮食安全与人口健康高峰论坛论文集  2012-08-14 下载次数(8)| 被引次数(0)

A novel C-type lectin from the shrimp Litopenaeus vannamei possesses anti-WSSV activity 

C-type lectins play key roles in pathogen recognition,innate immunity and cell-cell interactions.Here,we report a new C-type lectin(LvCTL1) from the shrimp L...
第五届广东、湖南、江西、湖北四省动物学学术研讨会论文…  2008-11-01 下载次数(11)| 被引次数(0)

Lectin array to detect ionizing radiation-induced changes in cell surface glycans 

Background: Our goal is to identify specific markers on the endothelial surface of human brain arteriovenous malformations(AVMs) induced by ionizing radiation t...
第十届全国化学生物学学术会议报告摘要集  2017-09-23 下载次数(2)| 被引次数()

Purification,Characterization and Molecular Cloning of a Novel Mannose-Binding Lectin from Rhizome of Ophiopogon Japonicus with Antiviral and Antifungal Activities 

A novel mannose-binding lectin(designated OJL)was purified from rhizomes of Ophiopogonjaponicus by ion exchange chromatography on DEAE-Sepharose and gel filt...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(12)| 被引次数(0)

A Novel Mannan-binding Lectin from Clematis Montana Buch.-Ham Induces Apoptosis in L929 Cells 

A novel mannan-binding lectin(designated CML)was isolated from Clematis montana Buch.-Ham stem (Ranunculaceae)using ion exchange and gel filtration chromatog...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(4)| 被引次数(0)

Comprehensive Profiling of Accessible Surface Glycans of Mammalian Sperms Using a Lectin Microarray 

It is well known that cell surface glycans or glycocalyx play important roles in sperm motility,maturation and fertilization.A comprehensive profile of the sper...
中国生物化学与分子生物学会第十一次会员代表大会暨2014…  2014-08-21 下载次数(3)| 被引次数(0)

Mannan-binding lectin ameliorates hepatocellular carcinoma growth in mice 

Introduction:Hepatocellular carcinoma(HCC) is one of the most prevalent cancers and the most frequent cause of cancer-related death worldwide.Mannan-binding lec...
第十二届全国免疫学学术大会摘要汇编  2017-10-26 下载次数(3)| 被引次数()

Mannan-binding lectin Suppresses Peptidoglycan-induced Inflammatory Responses through the TLR2 Receptor,p38,JNK,and NF-κB Pathways 

Background:Peptidoglycan(PGN),the major cell wall component of Gram-positive bacteria,is known to elicit excessive proinflammatory cytokine production from immu...
第九届全国免疫学学术大会论文集  2014-10-18 下载次数(9)| 被引次数(0)

Association of mannan-binding lectin gene polymorphisms with progression of severe lupus nephritis 

Objective To investigate the association of single nucleotide polymorphisms(SNPs)of the mannan-binding lectin(MBL)gene with serum levels,development,progress...
《China Medical Abstracts(Internal Medicine)》  2014年 第02期 下载次数(9)| 被引次数(0)

Diet-induced reconstruction of mucosal microbiota associated with alteration of epithelium lectin expression and regulation in maintenance of rumen homeostasis 

Objective The mucosal microbiota in the gastrointestinal(GI) tract plays a pivotal role in local and systemic host physiology.Lectins are evolutionally conserve...
中国生理学会内分泌代谢、比较生理与应激生理学术会议论…  2017-07-13 下载次数(7)| 被引次数()

Isolation,Characterization and Molecular Cloning of a Mannose-binding Lectin from Arisaema Erubescens 

Arisaema erubescens agglutinin(AEA)from the tubers of Arisaema erubescens is a monocot mannose- binding lectin that catalytically agglutinated rabbit erythro...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(11)| 被引次数(0)

绵羊甘露糖结合凝集素基因(MBL)与支原体肺炎的相关性研究 

甘露糖结合凝集素(mannose-binding lectin, MBL)是一种由肝脏合成和分泌的急性期蛋白,属于胶原凝集素家族,广泛存在于肝脏及血液中。MBL通过激活补体和调理吞噬作用在抗感染的起始阶段起主导作用,是一种重要的天然免疫防御分子。MBL生物学功能的实现有赖于其完整的蛋白质结构,MBL结构基因突变影响了蛋...
石河子大学  博士论文  2011年 下载次数(406)| 被引次数(8)

甘露聚糖结合凝集素对T淋巴细胞免疫功能调节作用的初步研究 

天然免疫系统是由多种识别及效应分子组成的复杂的网络结构,通过模式识别受体如Toll样受体(Toll-like receptor, TLR)、肽聚糖识别蛋白、甘露聚糖结合凝集素(mannan-binding lectin, MBL)等识别病原相关分子模式(pathogen associated molecular pat...
南方医科大学  博士论文  2011年 下载次数(782)| 被引次数(2)

Characterization and expression patterns of mannose-binding lectin(MMBL) gene in mulberry(Morus multicaulis) and its prokaryotic expression in E.coli 

Mannose-binding lectin(MBL) is an important natural immune molecule which plays a significant role in plant self-defense and shows a broad spectrum resistance o...
2017中国长三角遗传学大会会议手册  2017-10-27 下载次数(4)| 被引次数()

Mannan Binding Lectin inhibits Proximal T cell Receptor Signaling and Suppresses Human T Cell Activation and Proliferation 

MBL initially described to recognize pathogenic microorganisms and activate complement pathway is also known to be involved in clearance of apoptotic cells and ...
第十一届全国免疫学学术大会摘要汇编  2016-11-04 下载次数(3)| 被引次数(0)

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