First evidence of proteinG-binding protein in the most primitive vertebrate:Serum lectin from lamprey(Lampetra japonica) 

Intelectins are a recently identified extracellular animal lectin as a glycan-binding receptors that recognize glycan epitopes on foreign pathogens and in the h...
遗传学进步促进粮食安全与人口健康高峰论坛论文集  2012-08-14 下载次数(8)| 被引次数(0)

Purification,Characterization and Molecular Cloning of a Novel Mannose-Binding Lectin from Rhizome of Ophiopogon Japonicus with Antiviral and Antifungal Activities 

A novel mannose-binding lectin(designated OJL)was purified from rhizomes of Ophiopogonjaponicus by ion exchange chromatography on DEAE-Sepharose and gel filt...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(12)| 被引次数(0)

A Novel Mannan-binding Lectin from Clematis Montana Buch.-Ham Induces Apoptosis in L929 Cells 

A novel mannan-binding lectin(designated CML)was isolated from Clematis montana Buch.-Ham stem (Ranunculaceae)using ion exchange and gel filtration chromatog...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(4)| 被引次数(0)

Comprehensive Profiling of Accessible Surface Glycans of Mammalian Sperms Using a Lectin Microarray 

It is well known that cell surface glycans or glycocalyx play important roles in sperm motility,maturation and fertilization.A comprehensive profile of the sper...
中国生物化学与分子生物学会第十一次会员代表大会暨2014…  2014-08-21 下载次数(3)| 被引次数(0)

Diet-induced reconstruction of mucosal microbiota associated with alteration of epithelium lectin expression and regulation in maintenance of rumen homeostasis 

Objective The mucosal microbiota in the gastrointestinal(GI) tract plays a pivotal role in local and systemic host physiology.Lectins are evolutionally conserve...
中国生理学会内分泌代谢、比较生理与应激生理学术会议论…  2017-07-13 下载次数(7)| 被引次数()

Isolation,Characterization and Molecular Cloning of a Mannose-binding Lectin from Arisaema Erubescens 

Arisaema erubescens agglutinin(AEA)from the tubers of Arisaema erubescens is a monocot mannose- binding lectin that catalytically agglutinated rabbit erythro...
2008年全国生物化学与分子生物学学术大会论文摘要  2008-10-01 下载次数(11)| 被引次数(0)

A novel mannan-binding lectin from Clematis montana Buch.-Ham induces apoptosis in L929 cells 

The objective of this study was to isolate a novel lectin from Clematis montana Buch.-Ham stem(Ranunculaceae) and examine it for various biological activitie...
2008年全国糖生物学学术会议论文摘要  2008-06-01 下载次数(9)| 被引次数(0)

甲壳类C-型凝集素的功能研究 

无脊椎动物缺少传统意义上的适应性免疫,但是具有快速高效的先天免疫系统,用来防御微生物的侵袭。由于病原微生物表面具有较为保守的病原相关分子模式(pathogen-associated molecule patterns, PAMPs),所以无脊椎动物的模式识别蛋白(pattern recognition receptor...
山东大学  博士论文  2011年 下载次数(675)| 被引次数(9)

囊丝黄精(Polygonatum cyrtonema Hua.)离体再生体系的建立和活性成分分析、黄精凝集素Ⅱ基团特异性化学修饰与生物学活性及其基因的克隆与表达研究 

百合科植物囊丝黄精(Polygonatum cyrtonema Hua.)是我国传统中草药,其根状茎中含有一种凝集素,命名为黄精凝集素Ⅱ(Polygonatum cyrtonema Hua.Lectin Ⅱ,简称PCLⅡ),具有特异性结合甘露糖和唾液酸以及凝集兔红细胞、促T细胞有丝分裂等活性。利用...
四川大学  博士论文  2003年 下载次数(406)| 被引次数(3)

Molecular cloning and functional characterization of the C-type lectin 4 from Sinonovacula constricta 

C-type lectin receptors(CLRs) are important pattern recognition molecules that could recognize carbohydrates from pathogen,then participate in bacterial binding...
浙江省第四届动物学博士与教授论坛、动物学与经济强省-…  2017-11-17 下载次数(4)| 被引次数()

Molecular Modeling,docking and dynamic simulation of GNA-related lectins for potential prevention in influenza virus(H1N1) 

Galanthus nivalis agglutinin(GNA)-related lectin family,as a mannose or sialic acid specific lectin family, exhibits significant anti-HIV and anti-HSV proper...
中国生物化学与分子生物学会第十届会员代表大会暨全国学…  2010-08-23 下载次数(9)| 被引次数(0)

胶原凝集素-补体激活蛋白嵌合体 

本发明涉及能够激活补体系统的融合蛋白,所述融合蛋白包含源自凝集素-补体途径激活蛋白或其功能同系物的第一多肽序列;和源自胶原凝集素或其功能同系物的第二多肽序列;其中所述补体激活蛋白不是胶原凝集素。优选的融合蛋白包含图1的L-ficolin序列的氨基酸和图2所示MBL序列的氨基酸。所...
内蒂穆恩公司  中国专利  2005年 下载次数(0)| 被引次数(0)

小麦JRL凝集素基因的表达及TaJRL2.1的功能分析 

植物凝集素家族包含有储藏蛋白及与非生物胁迫耐性、病虫害抗性相关的功能蛋白等,是一个成员种类及数目均庞大的家族。JRL (Jacalin-related lectins)类凝集素是植物凝集素中的一种,具有一个或多个与来源于木菠萝(Artocarpus integrifolia)中的Jacalin凝集素类似的结构域,是一类...
南京农业大学  博士论文  2014年 下载次数(169)| 被引次数(0)

2种海洋无脊椎动物凝集素性质及其与微生物相互作用的研究 

凝集素通常被认为是非酶和非免疫的可促使细胞凝集的蛋白质或多价糖结合蛋白,广泛存在于动物、植物和微生物中。凝集素具有多种生物活性,与细胞间的粘着、细菌感染宿主、受体介导的胞饮、机体天然免疫防御、宿主巨噬细胞吞噬清除入侵细菌、精子与卵细胞的识别与结合等生理过程密切相关。凝集素已被广泛应用于多个研究领域,例如凝集素作为促有丝...
沈阳农业大学  博士论文  2011年 下载次数(429)| 被引次数(2)

Study of a New C-type Lectin with a Long Carbohydrate Recognition Domain(CRD)from Artemia Parthenogenetica 

C-type lectin is a family of Ca2+dependent carbohydrate-recognition proteins which play crucial roles in the innate immunity of invertebrates by mediating the r...
浙江大学  博士论文  2011年 下载次数(35)| 被引次数(0)

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