Genetic alterations in hepatocellular carcinoma: An update 

Hepatocellular carcinoma(HCC) is one of the leading causes of cancer-related deaths worldwide. Although recent advances in therapeutic approaches for treating H...
《World Journal of Gastroenterology》  2016年 第41期 下载次数(17)| 被引次数(12)

Communication and monitor of breast cancer signal in the pulse-output genetic circuit network 

Pulse-output genetic circuit networks have the advantages in stability and accuracy.In this paper,we analyze some important parameters in a typical inverter,and...
《Science China(Information Sciences)》  2014年 第03期 下载次数(75)| 被引次数(2)

Genetic immunotherapy ot hepatocellular carcinoma ( HCC) with adenovirus or retrovirus vectors carrying interleukin 12 ( IL-12 ) or costimulatory molecule B7-1 

The progressive growth of tumors in the presence ofan intact immune system suggests that immunemechanisms may have failed to defend the host fromtumor cells...
《实验血液学杂志》  1997年 第03期 下载次数(10)| 被引次数(0)

The origin of genetic risk for nasopharyngeal carcinoma:a commentary on Is nasopharyngeal cancer really a “Cantonese cancer”? 

Nasopharyngeal Carcinoma (NPC) occurs with highest incidence in Southeastern China among Cantonese-speaking Chinese, giving rise to the common name of Canto...
《癌症》  2010年 第05期 下载次数(32)| 被引次数(5)

Genetic analysis of CDKN2A gene inactivation in sporadic ovarian cancer 

Objective ThetumorsuppressorgeneCDKN2A,locatedonchromosome9p21,encodesthecellcycleregulatoryproteinp16.InactivationofCDKN2Agene
《Chinese Medical Journal》  1999年 第10期 下载次数(7)| 被引次数(0)

Survivin及COX-2基因与原发性肝细胞癌的关联研究 

原发性肝细胞癌(Hepatocellular Carcinoma, HCC)是一种复杂性疾病,遗传和环境因素在其发病中均起重要作用。本研究采用病例对照研究设计,应用聚合酶链反应(Polymorphism Chain Reaction, PCR)-限制性片段长度多态性(Restriction Fragment Lengt...
复旦大学  硕士论文  2011年 下载次数(127)| 被引次数(1)

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma 

The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The maj...
《World Journal of Gastroenterology》  2015年 第42期 下载次数(16)| 被引次数(4)

Genetic Polymorphism of the multidrug resistance 1 gene MDR1and the Risk of Hepatocellular Carcinoma 

Objective P-glycoprotein encoded by the multidrug resistance 1 gene(MDR1)has been demonstrated to play an important role in inflammation and carcinogenesis.G...
第八届中国肿瘤学术大会暨第十三届海峡两岸肿瘤学术会议…  2014-09-11 下载次数(7)| 被引次数(0)

Genetic testing vs microforceps biopsy in pancreatic cysts:Systematic review and meta-analysis 

BACKGROUND Carcinoembryonic antigen(CEA) and cytology in pancreatic cystic fluid are suboptimal for evaluation of pancreatic cystic neoplasms. Genetic testing a...
《World Journal of Gastroenterology》  2019年 第26期 下载次数()| 被引次数()

低频遗传变异与肺癌遗传易感性及预后关联研究 

肺癌是全球最常见的恶性肿瘤之一。目前其发病率和死亡率均位居全球范围内恶性肿瘤的首位。近年来,肺癌持续占据我国男性新发恶性肿瘤的首位,女性新发恶性肿瘤的第二位;而且由于肺癌预后差,在我国全肿瘤死因中,肺癌始终占据首位。过去数十年中,持续增长的烟草消费和不断加重的环境污染,导致我国多数地区的肺癌发病率和死亡率仍呈现不断上升...
南京医科大学  博士论文  2017年 下载次数(484)| 被引次数(4)

Nasopharyngeal carcinoma as a paradigm of cancer genetics 

The unusual incidence patterns for nasopharyngeal carcinoma(NPC) in China,Northeast India,Arctic Inuit,Peninsular and island Southeast Asia,Polynesian Islanders...
《癌症》  2011年 第02期 下载次数(44)| 被引次数(7)

Functional Polymorphisms in the TGF β1 Gene and Nasopharyngeal Carcinoma Susceptibility in a Chinese Population 

Background:Nasopharyngeal carcinoma(NPC) is multifactorial,and the genetic background may be a crucial etiologic factor.Transforming growth factorβ1(TGFβ1) i...
浙江省医学会耳鼻咽喉科学分会成立60周年庆典暨2011年浙…  2011-09-01 下载次数(6)| 被引次数(0)

Crystal structure of human esterase D: a potential genetic marker of retinoblastoma 

Crystal structure of human esterase D: a potential genetic marker of retinoblastoma;;人酯酶D (EC 3.1.1.1)是非特异性酯酶家族的一员,在人体脑、肝脏、肾等器官大量表达,它的功能主要是催化水解乙酰基团。其基因与成视网膜细胞瘤等...
中国科学院生物物理研究所  科技成果  2009年 下载次数(1)| 被引次数(0)

Reduced expression and genetic alterations of ING4 in human stomach adencarcinoma 

ING4 is a member of ING gene family and harbors the PHD domain and NLS domain.ING4 is reported to interact with tumor suppressor p53 and found to be involved...
遗传学进步与人口健康高峰论坛论文集  2007-11-01 下载次数(8)| 被引次数(0)

Genetic alterations of hepatocellular carcinoma by random amplified polymorphic DNA analysis and cloning sequencing of tumor differential DNA fragment 

AIM: To study the genetic alterations and their association with clinicopathological characteristics of hepatocellular carcinoma (HCC), and to find the tumor...
《World Journal of Gastroenterology》  2005年 第26期 下载次数(7)| 被引次数(3)

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