In Vivo Screen Strategies for Discovering Bioactive Compounds Against Cerebrovascular and Neurodegenerative Diseases 

Cerebrovascular and neurodegenerative diseases are tightly associated with each others and are increasing harmful to our health and life.The global disease p...
第十四届全国中药和天然药物学术研讨会论文摘要  2014-08-26 下载次数(3)| 被引次数(0)

Antioxidant activity and the bioactive compounds of methanol extracts of white jelly mushroom,Tremella fuciformis 

White jelly mushroom(Tremella fuciformis) has been used in traditional China medicine.The following antioxidant activities of subfractions from the methanol ...
中国菌物学会第五届会员代表大会暨2011年学术年会论文摘…  2011-08-15 下载次数(24)| 被引次数(0)

Fast and effective target identification of the bioactive compounds form the medicinal plants via computational chemical biology approach 

The potential drug target database(PDTD) was searched by TarFisDock server,a reverse docking approach,to identify putative targets for a collection of 19 nat...
2011年全国药物化学学术会议——药物的源头创新论文摘要…  2011-11-17 下载次数(8)| 被引次数(0)

Chemical diversity and the bioactive compounds from marine invertebrates inhabited in South China Sea 

China holds a long coastline(approximately 18,000 km) and covers three different climatic zones ranging from temperate to tropical regions.Its coastal waters...
中国化学会第9届天然有机化学学术会议论文集  2012-11-08 下载次数(33)| 被引次数(0)

LDH-A inhibitory activity guided isolation of bioactive compounds from Spatholobus suberectus 

Objective:To screen out the potential LDH-A(Lactate dehydrogenase A,a novel potential molecular target for cancer therapy) inhibitors from Spatholobus subere...
中国化学会第9届天然有机化学学术会议论文集  2012-11-08 下载次数(12)| 被引次数(0)

Screebubg if actuve cinibebts in Angelica sinensis by using biomembrane affinity extraction coupled with high performance liquid chromatography 

ABSTRACTThe screening and analysis of bioactive components in tradifional Chinese medicines (TCMs) is very important not orly forthe quality control of crude...
中国药理学会制药工业专业委员会第十一届学术会议论文摘…  2004-06-30 下载次数(9)| 被引次数(0)

GC–MS analysis of bioactive compounds present in different extracts of an endemic plant Broussonetia luzonica (Blanco) (Moraceae) leaves 

Objective: To investigate and characterize the chemical composition of the different crude extracts from the leaves of Broussonetia luzonica(Blanco)(Moraceae)(B...
《Asian Pacific Journal of Tropical Biomedicine》  2016年 第11期 下载次数(9)| 被引次数(1)

噻唑类新化合物的设计与合成及其抗微生物活性研究 

噻唑环是一类含有氮硫杂原子的重要五元芳香杂环,具有富电子性,易通过氢键、配位键、π-π堆积、范德华力、静电和疏水作用等多种非共价键与生物体内的多种酶、蛋白质、核酸及其他活性位点发生作用,表现出多种生物活性,因此噻唑环被广泛用于药物设计与开发。随着众多噻唑类化合物成功用于临床,如抗生素药物头孢、抗癌药物达沙替尼、消炎药物...
西南大学  博士论文  2018年 下载次数(183)| 被引次数()

新型唑类化合物的设计合成及其相关抗微生物活性研究 

唑类化合物是一类重要的富电子含氮杂环化合物。其特殊的结构使得唑类衍生物易于与有机生命体中的酶和受体发生多种非共价相互作用,如氢键、配位键、离子偶极、阳离子-?、?-?堆积、疏水作用以及范德华力等,因此在药物化学领域应用非常广泛,其抗微生物性质尤为突出,如噻唑和咪唑类化合物。本文基于噻唑和咪唑化合物在国内外的研究与开发现...
西南大学  硕士论文  2016年 下载次数(94)| 被引次数(0)

Cell Affinity Capture and HPLC-MS Analysis for Anticardiovascular Diseases Drug Screening from Danshen 

This manuscript develops a novel high-throughput analysis and screening method of cell affinity capture coupled with HPLC-mass spectrometry analysis(CAC-HPLC-MS...
第二十届全国色谱学术报告会及仪器展览会论文集(第三分…  2015-04-19 下载次数(7)| 被引次数(0)

Bioactive Diphenyl Ether Derivatives from a Marine-Derived Talaromyces sp.Fungus 

Marine-derived fungi have proven to be rich sources of structurally novel and biologically active secondary metabolites for drug discovery.There have been an in...
全国第九届海洋生物技术与创新药物学术会议论文摘要集  2014-08-06 下载次数(12)| 被引次数(0)

Phenolic compounds from Merremia umbellata subsp.orientalis and their allelopathic effects on arabidopsis seed germination 

A bioassay-directed phytochemical study was carried out to investigate potential allelochemicals of the invasive plant Merremia umbellata subsp.orientalis(Ha...
第三届全国生物入侵大会论文摘要集——“全球变化与生物…  2010-11-26 下载次数(12)| 被引次数(0)

Natural quinone reductase inducers from Xinjiang special plants 

The malignant tumor is still the leading disease threatening the human life and health at present.More and more attention has been caused on cancer chemoprev...
2011年全国药物化学学术会议——药物的源头创新论文摘要…  2011-11-17 下载次数(5)| 被引次数(0)

The Neuropharmacological Effects of Herba Epimedii and its Main Bioactive Components:Icariin,Icariside Ⅱ and Icartin 

Herba Epimedii,a traditional & Chinese medicine(T&CM),is used as a tonic,remedy for calming the nerves and anti-rheumatic agent in some Chinese proprietary medi...
《神经药理学报》  2017年 第02期 下载次数(10)| 被引次数()

超声在梨汁加工中的应用 

梨(Pyrus bretschneideri R.)是产量较大的温带水果,仅次于葡萄及苹果。其中,中国的梨产量占世界产量的70%以上。在中国,梨作为传统药物使用已有2000多年历史,具有抗炎、抗高血糖及利尿等功效。相比苹果,梨具有较低的钠含量、较高的钾含量及低酸性性质使其成为高酸性食品及婴儿食品的常见成分。热处理是食品...
南京农业大学  博士论文  2016年 下载次数(67)| 被引次数(1)

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